Alzheimer's - 1PBQ-Q1 - N-Methyl-D-Aspartate (NMDA) receptor

Proteome
1PBQ-Q1
N-Methyl-D-Aspartate ( NMDA ) receptor

N-Methyl-D-Aspartate (NMDA) antagonists are recognised as potentially useful as a therapy for Alzheimer's Disease - see DDT (2005) 10.11 p 750. Over stimulation of this receptor appears to be related to neurodegeneration and blocking it has some therpeutic benefits. This approach is rather different from many of the other Alzheimer's Disease drugs which are being developed.

The test jobs times usually took longer than average and giving more hits.


H Furukawa and E Gouaux EMBO J (2003) 22.12 p2873-85