Proteome - 4PRG-Q1 - anti-diabetic, anti-obesity

Proteome
4PRG-Q1
Peroxisome proliferator-activated receptor g(PPAR-g)

The peroxisome proliferator-activated receptors g(PPAR-g) are ligand-activated transcription factors belonging to the nuclear receptor family. The therapeutic potential of this receptor is not fully appreciated. It has been suggested that this is a possible target for anti-obesity drugs and anti-diabetic - although some selectivity may be required.
This query is based on a different crystal structure to 1i7i-q1.

The test jobs times were typical giving normal numbers of hits.


P Cronet et al Structure (2001) 9.8 p699-706