Cancer - 1PME-Q1 - Mitogen Activated Protein (MAP) Kinase

Cancer
1PME-Q1
Mitogen Activated Protein (MAP) Kinase

Mitogen Activated Protein (MAP) Kinases are signaling proteins that participate in diverse cellular events and are potential targets for intervention in inflammation, cancer, and other diseases. The MAP kinase this query is based on is known as ERK2 (extracellular-signal-regulated kinase 2) and plays a role in cellular differentiation or proliferation. This query is based on a different crystal structure to 3erk-q1 and 4erk-q1.

For this query the times taken by test jobs and numbers of hits were above average.


Z Wang et al Structure (1998) 6.9 p1117-28