Thursday, August 11, 2005

Cancer - 4ERK-Q1 - Mitogen Activated Protein (MAP) Kinase

Cancer
4ERK-Q1

Mitogen Activated Protein (MAP) Kinase

Mitogen Activated Protein (MAP) Kinases are signaling proteins that participate in diverse cellular events and are potential targets for intervention in inflammation, cancer, and other diseases. The MAP kinase this query is based on is known as ERK2 (extracellular-signal-regulated kinase 2) and plays a role in cellular differentiation or proliferation. This query is based on a different crystal structure to 3erk-q1.

For this query the times taken by test jobs were below average giving typical numbers of hits.

Z Wang et al Structure (1998) 6.9 p1117-28

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