Friday, September 30, 2005

Methodology - 1H9Z-Q1 - Serum Albumin

Methodology
1H9Z-Q1

Serum Albumin

Serum albumin is an important transport protein in the blood playing a key role in the transport of fatty acids, metabolites, and some drugs. However, one might expect undesirable side-effects from molecules which bind strongly. In addition, such molecules are likely to show exceptional pharmacokinetics with abnormally long retention times in the body. This query is based on an alternative site in a different protein crystal structure to 1e7a-q1.

This query gave above average numbers of hits and job times

I Petitpas et al J Biol Chem (2001) 276 p22804

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