Alzheimers - 1U7T-Q1 - ABAD (aka HSD10 )

Proteome
1U7T-Q1
Amyloidβ-Peptide- Binding Alchohol Dehydrogenase (ABAD)

Amyloidβ-Peptide- Binding Alchohol Dehydrogenase (ABAD) is also known as 17β-hydroxysteroid dehydrogenase type 10 (HSD10). It has been implicated in the development of Alzheimer's disease. ABAD binds to βamyloid and plays a role in the neurotoxicity. An inhibitor which stops this binding might be useful therapeutically in the treatment of Alzheimers disease.

We expect most jobs for this query to take longer than average giving more hits than usual.


C R Kissinger et al J Mol Biol (2004) 342.3 p943-52