Multiple Sclerosis - 1F45-Q3 - Human Interleukin-12B

Multiple Sclerosis
1F45-Q3
Human Interleukin-12B

Interleukin-12B (IL-12B) belongs to the cytokine class of proteins and is crucial for the generation of immunity to intracellular pathogens. It is known to stimulate production and enhance the activity of natural killer cells and T cells, and to induce production of interferon. It is important in preventing infection by intracelluar bacteria and parasites. IL-12B also contributes to various immunopathological conditions, so understanding its role may lead to new therapies for rheumatoid arthritis, multiple sclerosis and other autoimmune diseases. This query targets a variant of the site used in 1f42 -q2 .


C Yoon, S C Johnston, J Tang, M Stahl, J F Tobin and W S Somers Embo Journal 19 p3530 (2000)