Tuesday, June 21, 2005

Cancer - 1XKK-Q1 - ErbB1 ( EGFR )

Cancer
1XKK-Q1

ErbB1

In cancer cells, the ErbB1 receptor tyrosine kinase (also known as EGFR) is sometimes present in higher concentrations than normal. ErbB1 (like ErbB2) is an important signally protein and stimulation leads to growth of the tumour. It may therefore be an important anti-cancer drug target.

We expect this queries to give many hits with job times longer than average.


E R Wood et al Cancer Res (2004) 64.18 p6652-9

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