Diabetes - 1LQF-Q1 - Protein-Tyrosine Phosphatase 1B (PTP1B)

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1LQF-Q1
Protein-Tyrosine Phosphatase 1B (PTP1B)

It has been suggested that inhibitors of Protein-Tyrosine Phosphatse 1B (PTP1B) could be therapeutically beneficial in the treatment of type 2 diabetes. However, as there are many other phosphatases in the cell it is necessary to find selective inhibitors. Phosphatases have also been suggested as targets for other diseases.

The test jobs times were typical giving above normal numbers of hits.


E Asante-Appiah et al Biochemistry (2002) 41 p9043-51