1M2R-Q1 - Extended Cancer Query

This query has been extended to a larger set of mollecules, this normally means the small set has been good and they want MORE! ;-)

Cancer
1M2R-Q1
Casein Kinase 2

Protein kinases play key roles in signal transduction and therefore are among the most attractive targets for drug design. Casein Kinase 2 (CK2) is implicated in a variety of cellular functions and misfunctions. In tumours it is often present in abnormally higher concentrations, suggesting that inhibition may be of therapeutic value.

In tests, jobs took longer than typical jobs and gave more hits than usual.
They average around 16 to 24hrs per job for the first set


E De Moliner et al J Biol Chem (2003) 278.3 p1831-6