Alzheimer - 1UTT-Q1 - Macrophage Elastase

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1UTT-Q1
Metalloproteinase-12 ( MMP-12 )

Metalloproteinase-12 (Mmp-12) is also known as Macrophage Elastase and has been suggested as a possible drug target in the treatment of Alzheimer's disease. MMP-12 is also known to play a role in inflammatory processes including emphysema reducing lung function and also in Multiple Sclerosis where it may mediate the deposition of Amyloid proteins.

Job times for this query varied sometimes taking longer than typical jobs and giving above average numbers of hits.


R Morales et al J Mol Biol (2004) 341 p1063