Antibacterial - 1KIJ-Q1 - Gyrase B

Proteome
1KIJ-Q1
Gyrase B

Gyrase is a recognised antibacterial target. However, existing inhibitors have not had therpeutic potential because of serious side-effects and mutant resistance. It may be possible to find alternative inhibitors which do not have these limitations. This query is based on an alternative crystal structutre to 1aj6-q1.

Job times for this query varied often giving above average numbers of hits.

A Tanitame et al J Med Chem (2004) 47.14 p3693-6