AntiBacterial - 1KZM - Gyrase B

Proteome
1KZM-Q1
Gyrase B

Gyrase is a recognised antibacterial target. However, existing inhibitors have not had therpeutic potential because of serious side-effects and mutant resistance. It may be possible to find alternative inhibitors which do not have these limitations. This query is based on a different crystal structure to 1a6j-q1.

Job times for this query varied with some jobs taking less time and giving fewer hits than average jobs.

A Tanitame et al J Med Chem (2004) 47.14 p3693-6