New Query - Cancer - 1S9J-Q1

This is the MEK1 version of 1S9I-Q1 (which was MEK2)

Cancer
1S9J-Q1
Mitogen-Activated Protein Kinase 1 (MEK1)

Mitogen-Activated Protein Kinase 1 (MEK1) is a tyrosine/threonine protein kinases found in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathway. This growth pathway is activated in many cancers and inhibiting it might be a useful cancer therapy for certain tumours.

In test jobs the time taken varied but was often longer than 1S9I-Q1 (MEK1) giving at least typical numbers of hits.


J F Ohren et al Nat Struct Mol Biol (2004) 11.12 p1192-7