Methodology - 1DMW-Q1 - Phenylalanine hydroxylase

Methodology
1DMW-Q1
Phenylalanine hydroxylase

This is one of several metabolic proteins which may cause undesirable side-effects if a drug interaction occurs. Phenyalanine hydroxylase (PAH) deficiency results in intolerance to the dietary intake of the essential amino acid phenylalanine and produces a spectrum of disorders including phenylketonuria (PKU), non-PKU hyperphenylalaninemia (non-PKU HPA), and variant PKU. A side-effect or drug interaction could cause similar symptoms.

The jobs times are expected to be slightly shorter than typical giving above average numbers of hits.



H Erlandsen et al Biochemistry (2000) 39.9 p2208-17