AntiBacterial - 1B70-Q1 - Phenylalanyl-tRNA synthetase

Proteome
1B70-Q1
Phenylalanyl-tRNA synthetase

Phenylalanyl-tRNA synthetase is an essential enzyme which catalyses the transfer of phenylalanine to the Phe-specific transfer RNA. Inhibitors of this enzyme have potential to be a new class of antibiotic which can be used against bacterial infection which do not respond to other antibiotics. This query is based on a different crystal structure to 1b7y-q2.

Some jobs for this query take longer than usual giving above average numbers of hits.

D Beyer et al Antimicrob Agents Chemother (2004) 48.2 p525-32