Cancer - 1XBC-Q1 - Syk Tyrosine Kinase ( SYK )

Cancer
1XBC-Q1
Syk Tyrosine Kinase

Many Tyrosine Kinases including SYK are inhibited by some anti-cancer drugs. Tyrosine Kinases are also associated with rheumatoid arthritis, inflammation and immunological responses. A lack of selectivity might cause undesirable side-effects and prohibit long term use as preventative treatment. This query is based on a different crystal structure to 1xbb-q1.

We expect jobs for this query to give than typical numbers of hits in longer than average times.


S Atwell et al J Biol Chem (2004) 279 p55827-32