Cancer - 1Y6B-Q1 - Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)

Cancer
1Y6B-Q1
Vascular Endothelial Growth Factor Receptor 2 ( VEGFR2 )

VEGF stimulates the growth of blood vessels. The uncontrolled growth of cancer cells is legendary. But this sort of growth requires a lot of blood flow to the cell area. If the blood vessel growth can be restrained, then, in theory, so can growth of the tumour. This query is based on a different crystal structure to 1y6a-q1.

The times for test jobs of this query were typical and gave average numbers of hits.


P A Harris et al J Med Chem (2005) 48 1610