Tuesday, September 06, 2005

Hepatitis C - 1DY8-Q1 - Hepatitis C Virus NS3 Serine Protease

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1DY8-Q1

Hepatitis C Virus NS3 Serine Protease

NS3 serine protease expressed by the hepatitis C virus is a recognised target for drug design. While some high molecular mass peptides have worked in the laboratory they are not suitable as drugs and the search for typical drug-like molecule has been less successful. This query is based on a different crystal structure to 1DY9-Q2.

The time taken by test jobs was variable usually giving fewer hits than average with most jobs completing relatively quickly.

S Di Marco et al J Biol Chem (2000) Vol 275, p7152

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