Alzheimer's - 1TQF-Q1 - Beta-secretase (Memapsin 2)

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1TQF-Q1
Beta-secretase ( Memapsin 2 )

Beta-secretase is a recognised drug design target for Alzheimer's disease for which peptide inhibitors are already known. Such inhibitors are of little clinical use because of their high molecular mass. This query is based on a different crystal structure to 1fkn-q3, 1m4h-q2 and 1sx7-q1.

Test jobs for this query gave more hits than average with jobs taker longer than usual.


L Hong et al Science (2000) 290 p150