Tuesday, November 22, 2005

Cancer - 1O4P-Q1 - C-SRC Tyrosine Kinase

Cancer
1O4P-Q1

C-SRC Tyrosine Kinase

Tyrosine kinases occur widely in human tissues. Achieving selectivity is important to avoid side-effects especially if a drug is to be taken for a long period of time. C-SRC tyrosine kinase is a recognised anti-cancer drug target. This query is based on a different crystal structure to 1lcj-q1.

The job times for test queries varied sometimes taking longer average jobs and giving more hits.

L A Witucki et al Chem Biol (2002) 9.1 p25-33

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