Monday, November 28, 2005

Cancer - 1BQO-Q1 - Stromelysin

Cancer
1BQO-Q1

Stromelysin

Stromelysin belongs to the class of Matrix MetallogProteinases (MMPs). It is a recognised anti-cancer target which is associated with tumour blood supply although finding clinically effective molecules has proven difficult. This query is based on a different protein crystal structure to 1b8y-q1 and 1biw-q1.

The times for test jobs were variable often giving more hits than average.

R C Rizzo et al J Med Chem (2004) 47.12 p3065-74

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