Cancer - 1I4O-Q1 - X-linked Inhibitor of Apoptosis Protein (XIAP)

Cancer
1I4O-Q1
X-linked Inhibitor of Apoptosis Protein (XIAP)

Inhibitor of Apoptosis proteins are often present in exceptionally high quantities in cancer tissues. It is believed that molecules which bind to X-linked Inhibitor of Apoptosis Protein (XIAP) induce cell death by freeing caspases.

The job times for test queries varied with most giving typical numbers of hits.

K Thorsten et al J Med Chem (2004) 47.18 p4417-26